What are Quinoline derivatives?
Among heterocyclic compounds, Quinoline is a privileged scaffold that appears as an important construction moiety for the development of new drugs. Quinoline nucleus is endowed with a variety of therapeutic activities and new Quinoline derivatives known to be biologically active compounds possessing several pharmacological activities. Many new therapeutic agents have been developed by using Quinoline nucleus .
Hence Quinoline and its derivatives form an important class of Heterocyclic compounds for new drug development. Numerous synthetic routes have been developed for the synthesis of Quinoline and its derivatives due to its wide range of biological and pharmacological activities. The various Quinoline derivatives are used in synthesis of drugs such as antimalarial, anticancer, antibacterial, anthelmintic, antiviral, antifungal, anti-inflammatory, analgesic, cardiovascular, central nervous system, hypoglycemic and miscellaneous activities.
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